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Last reviewed July 16, 2026

Disodium ribonucleotides (E635)

E635 is not one additive but two working together: disodium inosinate plus disodium guanylate. Its vegan status is only as clean as the inosinate inside it.

Where it hides

  • Instant noodles and ramen
  • Crisps and savoury snacks
  • Seasoning blends and stocks
  • Usually with MSG (E621)

What it is

Disodium ribonucleotides, E635, is the workhorse umami booster in packaged savoury food. It is defined by its two components:

Primary source 01 / 01

It is a mixture of disodium inosinate (IMP) and disodium guanylate (GMP) and is often used where a food already contains natural glutamates (as in meat extract) or added monosodium glutamate (MSG).

Wikipedia encyclopedia entry Disodium ribonucleotides, 2025

Follow the inosinate

Since half the blend is disodium inosinate (E631), which is often extracted from meat or fish, E635 inherits that uncertainty. The guanylate half is fermentation-derived, but that does not clear the whole additive. Unless the manufacturer confirms a fermentation or plant source, treat E635 as uncertain.

Frequently asked

What is E635 made of?

It is a mixture of disodium inosinate (E631) and disodium guanylate (E627). Because the inosinate is often from meat or fish, E635 is uncertain unless the maker confirms a non-animal source.

Is E635 in most instant noodles?

It is very common in instant noodles, crisps and seasoning, usually alongside MSG. Its vegan status depends on how the inosinate portion was made.

The sources

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